The TGB Supplements Blog was created to keep everyone up to date on all of the latest and greatest supplement information. The TGB Supplements website ( www.tgbsupplements.com ) has over 6000+ products and is always growing. In that 6000+ products some of the supplements are good, some are bad, and some are ugly. We will use this blog to discuss all three types in great detail. We will showcase our latest and greatest hot products and break them down in a way that explains how they work.
Friday, January 20, 2017
Check Out The Anabolic Cartel Podcast!
Give the Anabolic Cartel Podcast a listen to here. A lot of solid Info with a no B.S. Vibe.
Monday, January 16, 2017
Friday, December 30, 2016
Testing some Compounds with the New Roidtest Kits
Check out our video on youtube testing out some compounds with the Roidtest Kits
Sunday, December 18, 2016
Nsaids and Protein Synthesis
NSAIDs and Muscle
Building
According to research published in the The Physician and
Sports Medicine, since NSAIDs are over-the-counter (OTC) medications and aren't
banned from competition by the World Anti-Doping Agency, "athletes often
self-administer these medications to prevent pain and inflammation before it
occurs. However, scientific evidence for this approach is currently lacking,
and athletes should be aware of the potential risks in using NSAIDs as a
prophylactic agent. These agents are not benign and can produce significant
side effects, including gastrointestinal and cardiovascular conditions as well
as musculoskeletal and renal side effects.
But that's not all: there are also performance side effects
for the weightlifter to consider. Drugs such as ibuprofen are classified as COX
inhibitors, and since COX (cyclooxygenase) activity is a critical component of
muscular hypertrophy, there's a clear link: Ibuprofen can inhibit muscular
hypertrophy.
In fact, previous research suggests that treatment with
ibuprofen can reduce muscle hypertrophy by almost 50 percent, which means that
taking a COX inhibitor may very well be counterproductive for muscle gains.
While these are intriguing findings, we must keep in mind
that these studies were conducted in rodent models. The research still needs to
be scrutinized since a handful of studies have also been done on humans and
have yielded conflicting results.
One of the first human studies to support the notion that
NSAIDs may blunt protein synthesis was published in the American Journal of
Physiology, Endocrinology, and Metabolism.4 Participants were given the maximal
over-the-counter dose for ibuprofen, acetaminophen, or a placebo following
10-14 sets of eccentric knee extensors.
Researchers found that rates of protein synthesis were
suppressed in groups taking the NSAIDs. Results from this study support the
earlier findings that NSAIDs may negatively influence protein metabolism in
skeletal muscle.
Research suggests that treatment with ibuprofen can reduce
muscle hypertrophy by almost 50 percent.
However, more recent research on human subjects has
demonstrated that NSAIDs do not necessarily impact muscle protein synthesis as
much as previously thought. In fact, there are several studies that have found
chronic supplementation (12 weeks) actually improved muscle strength and size.
The problem with these studies, however, is that each have
their own limitations we must consider. For example, a majority of the research
on NSAIDs as it relates to muscle protein synthesis has been done in untrained
individuals; hence, the results might yield a different outcome on athletes who
are already active and have a larger degree of muscle mass than an untrained
person.
Some of the research also looked at only older subjects with
osteoarthritis; thus, these results might not be indicative of results for
healthy, active individuals. Finally, some of these studies only looked at the
effects of NSAIDs on the acute changes in muscular hypertrophy, and these
findings may not reflect the long-term adaptations to muscular hypertrophy with
prolonged use of NSAIDs.
While there's certainly a time and place to utilize NSAIDs,
the key takeaway is that they should be used with caution, in relatively
moderate dosages, and for short periods of time.
An article published in the Critical Journal of Sport
Medicine discussed the practical management of NSAIDs in athletic injuries and
concluded that NSAIDs are not recommended in the treatment of completed
fractures, stress fractures at higher risk of nonunion, or in chronic muscle
injuries.
While the authors of the article recommended NSAIDs for the
management of acute ligament strains, muscle strains, tendinitis, and eccentric
muscle injury, they cautioned that the prescription of the NSAID should be
judicious and the length of treatment should be kept as short as possible.
NSAIDS can help with short-term pain management, but their
use should be minimized not only because of their potential long-term side
effects, but also the impact they may have on making substantial gains in
muscle mass.
Even with some conflicting research, this much is clear:
Don't reach for a bottle of ibuprofen every time you have a slight bout of
DOMS. Recognize that the inflammation you're experiencing is part of the
muscle-building process, and save NSAIDs for when you really need them.
In a nutshell, we need to keep anti-inflammatory to a
minimum to keep protein synthesis as high as possible to accumulate maximum
tissue in the shortest time possible.
Wednesday, December 14, 2016
Update! New health side effects on Rad-140
Friday, December 9, 2016
Tomatidine the next level of natural anabolics!
-Highly potent anabolic.
-Non-hormonal, thus no need for PCT or liver/cycle support.
-Heart-healthy, may assist with lipid and cholesterol support.
-Naturally extracted from the tomato plant.
-Complexed with shilajit for vastly enhanced solubility and bioavailability.
-Shilajit may assist with muscle growth and may provide testosterone support.
-Non-hormonal, thus no need for PCT or liver/cycle support.
-Heart-healthy, may assist with lipid and cholesterol support.
-Naturally extracted from the tomato plant.
-Complexed with shilajit for vastly enhanced solubility and bioavailability.
-Shilajit may assist with muscle growth and may provide testosterone support.
TITAN is Tomatidine --
simply the most potent natural anabolic available. [1-3] In a direct
comparison to ursolic acid, it was shown to be nearly 10-fold more
potent. It was also discovered to be nearly 5-fold more orally
bioavailable. It increases mTOR signalling in skeletal muscle, inhibits
the ATF4 pathway, and dramatically stimulates protein synthesis. Of
particular benefit to power athletes and bodybuilders is the fact that
it stimulates growth primarily in Type IIb and Type IIx muscle fibers --
the power fibers with the most potential for growth.
Although tomatidine is,
as previously mentioned, more orally bioavailable than ursolic acid, it
still displays extremely poor aqueous solubility -- estimated at
0.000189 mg/mL [4] -- which places hard limits on its oral
bioavailability. To sidestep this issue, we've complexed tomatidine
with shilajit. Shilajit, which has been used as a tonic and
rejuvenating agent for centuries, is a fully water-soluble mixture of
fulvic acids, humic acids, and minerals. Much like cyclodextrins, it is
capable of binding small molecules like tomatidine and forming
amorphous, water-soluble complexes. [5-7] Our tomatidine-shilajit
complex is orders of magnitude more water-soluble than pure tomatidine, a
fact which boosts its bioavailability to heights otherwise out of
reach.
The fact that shilajit
has itself been shown to assist with muscle growth, and boost
testosterone levels in healthy young men, is just a bonus. [8-9]
As is the fact that tomatidine is proven heart-healthy, and may be able to assist with cholesterol and lipid support. [10-11]
...The important thing is that TITAN is the most potent natural anabolic available.
Accept no substitute.
TITAN has been rigorously tested, results are publicly available, and a
patent is pending. TITAN uses top-quality tomatidine (standardized to
over 95% purity) and shilajit (standardized to 50%+ fulvic acids).If your looking to take your physique to the next level and want to stay on the natural route then look nor think any further then titan
Get it Here at TGB Supplements https://www.tgbsupplements.com/product/antaeus-labs-titan/
Monday, December 5, 2016
Trenbolone The King Of Anabolics!
Trenbolone is probably the greatest anabolic of all time with repatitioning capabilities matched by none this compound can change your physique in a way no other anabolic or combo can. But this comes with a price as trenbolone can be not the most user friendly compound. Check out our video on how to get the most out of trenbolone and even if its for you!
Monday, November 28, 2016
LGD-3303 The Cutting Edge In The World Of Sarms!
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